It is defined as the part of the prefrontal cortex that receives projections from the magnocellular, medial nucleus of the mediodorsal thalamus, and is thought to represent emotion and reward in decision making. It gets its name from its position immediately above the orbitsin which the eyes are located. Considerable individual variability has been found in the OFC of both humans and non-human primates. A related area is found in rodents.
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